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From149US$ /night
Check-in
14Feb2026Select date
Check-out
15Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Property overview

43 Columbia Street, Orlando, Florida, United States, 32806
-
Close to Downtown Orlando
Great
8.9
9.1
/10
4.5
4.3
/5

Rooms and Suites

Hampton Inn & Suites Orlando/Downtown South-Medical Center has 126 air-conditioned rooms with refrigerators and LCD televisions. Rooms include comforts such as air conditioning, as well as free WiFi. All rooms feature two queen or one king-sized Hampton clean and fresh bed(R), a lap desk, and free WiFi. Rooms also have a flat-screen TV, small refrigerator, and coffee-making facilities. Conveniences include coffee/tea makers, irons/ironing boards, and phones with free local calls. Room options include king rooms with a refrigerator, flat-screen TV, coffee-making facilities, and ironing facilities. Queen rooms include a refrigerator, flat-screen TV, and coffee-making facilities. King studios feature a microwave, refrigerator, wet bar, flat-screen TV, coffee-making facilities, and a seating area with a sofa bed. Queen rooms feature a microwave, refrigerator, wet bar, a flat-screen TV, coffee-making facilities, and a seating area with a sofa bed. Accessible room options are also available. Connecting rooms are available upon request.

Dining at Hampton

Hampton Inn & Suites Orlando/Downtown South-Medical Center provides free continental breakfast. Hampton's On the Run Breakfast Bags are available Monday through Friday. Guests can grab a bite from the snack bar/deli.

Leisure and Recreation

Hampton Inn & Suites Orlando/Downtown South-Medical Center provides recreational amenities including an outdoor pool and a fitness center. Guests may also enjoy a fun Orlando break with the friendly service and local advice from hotel staff. Those wishing to experience the area's popular attractions can visit Universal Orlando Resort and Universal Studios Florida. Consider making time for The Wizarding World of Harry Potter(TM).

Location and Transportation

Located in Downtown Orlando, Hampton Inn & Suites Orlando/Downtown South - Medical Center is a good base to explore the numerous golf courses found just outside the city center. The hotel is within a 15-minute walk of Orange Avenue and walking distance to Arnold Palmer Hospital for Children. Landmarks nearby: Loch Haven Park - 2 km, St James Roman Catholic Cathedral - 2 km, Farmers' market shopping - 2 km, Lake Conway - 2 km, Camping World Stadium - 3 km, Sodo Shopping Center - 1 km, Orange County Regional History Center - 2 km, Shoppes of West Church Street - 1 km. The nearest airport is Orlando Executive Airport.

Hotel Services

Hampton Inn & Suites Orlando/Downtown South-Medical Center provides dry cleaning/laundry services, and a gym. The hotel features a business center and complimentary newspapers in the lobby. Meeting facilities include 1128 square feet of space consisting of conference space and meeting rooms for up to 35 people. Contactless Arrival with Hilton Honors app is available. Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and a first aid kit. The hotel is pet-friendly with a max weight of 75 lbs, max size: small. 1-4 night stay $75. 5+ night stay $125. 2 pets max. Self-parking is available for $15.00 per day.

“Hampton Inn & Suites Orlando places guests near the downtown core and Orlando Executive Airport. I noted the generous breakfast and pet-friendly policy; small pets are welcome. For families and business travelers, the location near the medical center adds practical value.”
Hotel logo
David MillerEditor, UsFlorida
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Choose your preferred room

The property features double rooms, family rooms, and suites, often including breakfast, free cancellation, and special offers
King Room Hearing Accessible
2 persons
390 sq. feet 
1 King-size bed
Shower
Queen Room Two Queen Beds
2 persons
305 sq. feet 
2 King Size Beds
Shower
King Room
2 persons
360 sq. feet 
1 King-size bed
Shower
King Room Sofa Bed Non-Smoking
2 persons
370 sq. feet 
1 King-size bed and 1 Sofa bed
Shower
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Calendar of room availability and rates

See current availability and pricing for your dates

Facilities

Amenities are designed to ensure comfort and memorable stays

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Snack bar

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's buffet

Spa & Leisure

  • Outdoor swimming pool
  • Sun loungers
  • Leisure/ TV room

Room features

  • Air conditioning
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Media

  • Flat-screen TV
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Hampton Inn & Suites Orlando/Downtown South - Medical Center Location

43 Columbia Street, Orlando, Florida, United States, 32806
Map view
43 Columbia Street, Orlando, Florida, United States, 32806
Nearby
Amusement Park
Delaney Street Playground
1800 ft
Hospital
Orlando Regional Medical Center
1000 ft
Orlando Regional-Lucerne
1500 ft
Hospital
Winnie Palmer Hospital for Women and Babies
1900 ft
Restaurants
Delaney's Tavern
1500 ft
1315 S Orange Ave
Lucy Bleuz Cafe
1800 ft
1321 Sligh Blvd
Incredibly Edible
1800 ft
1321 Sligh Blvd
Orlando Brewing
2200 ft
1301 Atlanta Avenue
Brick & Fire
2600 ft
1621 S Orange Ave Ste 108
Pizza Hut
2600 ft
1621 S Orange Ave
Subway
3200 ft
1742 S Orange Ave
7-Eleven
3500 ft
1823 S Orange Ave
Explore Orlando
Explore Orlando
Top Attractions
Activities
Dining
Entertainment
Orange County Regional History Center
20 minutes' walk
Historical exhibits covering Central Florida's past. Features rotating exhibits and free admission days.
Lake Eola Park
30 minutes' walk
Scenic park with a lake, walking trails, and swan boats. Ideal for picnics and enjoying outdoor concerts.
Downtown Orlando
25 minutes' walk
Vibrant urban area with shops, galleries, and nightlife, perfect for experiencing local culture and cuisine.
Dr Phillips Center for the Performing Arts
20 minutes' walk
Cultural venue hosting Broadway shows, concerts, and dance performances, appealing to all arts enthusiasts.
Biking at Lake Eola Park
30 minutes' walk
Biking paths surround the park; bike rentals available nearby. A great way to enjoy the beautiful scenery.
Yoga Classes
25 minutes' walk
Local studios offer a variety of classes for all levels, perfect for relaxation and wellness seekers.
Delaney's Tavern
6 minutes' walk
Casual spot known for hearty American dishes and a laid-back vibe, perfect for families and groups.
Lucy Bleuz Cafe
7 minutes' walk
A cozy café specializing in artisan sandwiches and salads. Vegan and gluten-free options available.
Orlando Brewing
8 minutes' walk
Local brewery offering craft beers with a relaxed atmosphere. Perfect for winding down after a busy day.
Amway Center
25 minutes' walk
Home to exciting sports events and concerts, making it a must-visit for entertainment lovers.
Mad Cow Theatre
20 minutes' walk
Local theater offering a range of performances including dramas and comedies. Great for an evening out.
Local transportation
City Centre
Orlando6 min  ·  1700 ft
Airports
Orlando Executive Airport (ORL)12 min  ·  4.6 mi
Orlando International Airport (MCO)28 min  ·  11.2 mi
Train
Church Street Station17 min  ·  4600 ft
Woodsmere Sub-Station15 min  ·  5.8 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site (reservation might be needed) at USD 18 per day.
Internet
is available in for free.
Breakfast
All visitors are offered a buffet breakfast for a fee. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Languages
Spanish
Number of floors:
6
Number of rooms:
126
FAQs
About Hampton Inn & Suites Orlando/Downtown South - Medical Center
What time is check-in and check-out at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Check-in is at 15:00 and check-out is at 11:00.
Is parking available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Private parking is available on-site for 18 USD per day, and reservation is needed.
What are some highlights of Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The hotel features free WiFi, a fitness center, an outdoor swimming pool, and a business center.
What dining options are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Complimentary hot breakfast is served daily, along with a snack bar.
Which nearby restaurants can guests find around Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Nearby restaurants include Lucy Bleuz Cafe and The Lucky Lure, both located 0.5 km away.
What room amenities are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Rooms include air conditioning, a flat-screen TV, a small refrigerator, and coffee-making facilities.
What is the distance from Hampton Inn & Suites Orlando/Downtown South - Medical Center to Orlando Executive Airport?
The hotel is located 5 km from Orlando Executive Airport.
Does Hampton Inn & Suites Orlando/Downtown South - Medical Center provide business services?
Yes, the hotel offers meeting spaces with audio-visual equipment and a business center.
What fitness facilities are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Guests can enjoy a fitness center and an outdoor swimming pool.
What additional breakfast options are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Hampton's On the Run Breakfast Bags are available Monday through Friday.
What is the hotel's policy on late check-out at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Late check-out options are available where applicable.
How far is Hampton Inn & Suites Orlando/Downtown South - Medical Center from local attractions?
The hotel is 2 km from Church Street Station and 1 km from Amway Center.

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