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From203US$ /night
Check-in
14Feb2026Select date
Check-out
15Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Property overview

4905 San Pablo Road South, Jacksonville, Florida, United States, 32224
-
Near the Mayo Clinic
Perfect
9.0
9.3
/10
4.5
4.4
/5

Rooms and suites

Residence Inn By Marriott Jacksonville-Mayo Clinic Area has 155 rooms with kitchens that include refrigerators and stovetops. Rooms provide air conditioning, a seating area, a flat-screen TV with satellite channels, a kitchen, a dining area, and a private bathroom. Bathrooms include a hairdryer and complimentary toiletries. Suites feature a fully equipped kitchen, a living area, complimentary Wi-Fi, a sofabed, and a 50- or 55-inch SMART HDTV with Netflix. Select suites include kitchenware, a dining area, and tea/coffee makers. All rooms offer complimentary wireless Internet access, a phone, a laptop-compatible safe, and a desk.

Dining and snacking

Guests can enjoy a buffet or an American breakfast. The hotel offers a grocery/convenience store. There is a lobby bar. Guests can relax with a beverage and a bite to eat at the lobby bar or the poolside bar. Barbecue facilities are available.

Leisure amenities

Residence Inn By Marriott Jacksonville-Mayo Clinic Area features an outdoor swimming pool and a 24-hour fitness center. The hotel offers recreational amenities including an outdoor pool and a 24-hour fitness center. Guests have access to a state-of-the-art fitness center. There is also a terrace. Guests are welcome to the complimentary reception, held on select days.

Location and transport

Residence Inn By Marriott Jacksonville-Mayo Clinic Area is less than 1 mile from the Mayo Clinic. Beaches Museum and History Park is 6 km away. Shipwreck Island Water Park and Adventure Landing Jacksonville Beach are 4 km away. The hotel is 10.8 mi from Mayport Naval Station, 29 km from Union, and 45 km from Jacksonville International Airport. Northeast Florida Regional Airport is the closest airport. There is a complimentary hourly shuttle from 7am-5pm. The hotel is a 2-minute drive from Mayo Clinic Florida and 9 minutes from St Johns Town Center.

Hotel services

Residence Inn By Marriott Jacksonville-Mayo Clinic Area provides a 24-hour front desk, a shuttle service, a business center, and complimentary Wi-Fi throughout the property. Featured amenities include a 24-hour business center, express check-out, and complimentary newspapers in the lobby. The hotel has facilities measuring 2678 square feet, including conference space. Concierge services and wedding services are available. Guests can inquire about post-treatment nursing care partnerships.

“In my opinion, this property stands out for its dedication to guest comfort, especially with suites designed for extended stays and those visiting the nearby Mayo Clinic. I particularly appreciate the pet-friendly environment and the availability of in-suite kitchens. It's my view that the focus on convenience, from complimentary breakfasts to the shuttle service, enhances its appeal for both medical and business travelers.”
Hotel logo
David MillerEditor, UsFlorida
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Choose your preferred room

The property features double rooms, family rooms, and suites, often including breakfast, free cancellation, and special offers
One-Bedroom Queen Suite Hearing Accessible
2 persons
560 sq. feet 
1 King-size bed and 1 Sofa bed
Coffee machine
Heating
King Studio Suite Sofa Bed Adapted Tub Mobility Accessible
2 persons
410 sq. feet 
1 King-size bed and 1 Sofa bed
Coffee machine
Heating
Queen Corner Suite
2 persons
650 sq. feet 
1 King-size bed and 1 Sofa bed
Shower
Coffee machine
King Studio Suite Sofa Bed Hearing Accessible
2 persons
410 sq. feet 
1 King-size bed and 1 Sofa bed
Coffee machine
Heating
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Calendar of room availability and rates

See current availability and pricing for your dates

Facilities

Amenities are designed to ensure comfort and memorable stays

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Fireplace
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Golf course

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Free shuttle service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Grocery shopping service
  • Shops/Commercial services

Dining

  • Bar/ Lounge area
  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's buffet
  • Board games

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Heated swimming pool
  • Outdoor swimming pool
  • Sun loungers
  • BBQ facilities
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Dining table

Bathroom

  • Free toiletries
  • Sink

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Residence Inn By Marriott Jacksonville-Mayo Clinic Area Location

4905 San Pablo Road South, Jacksonville, Florida, United States, 32224
Map view
4905 San Pablo Road South, Jacksonville, Florida, United States, 32224
Nearby
Hospital
Mayo Clinic Jacksonville
3400 ft
Restaurants
Bundy Cafe & Atrium
3000 ft
4500 San Pablo Rd S Mayo Clinic
Explore Jacksonville
Local Experiences Near Residence Inn Jacksonville-Mayo Clinic Area
Top Attractions
Activities
Dining
Entertainment
Mayo Clinic Jacksonville
15 minutes' walk
Esteemed medical facility known for its advanced healthcare services, tours available for interested visitors.
Harbor City Municipal Golf Course
5 minutes' drive
Challenging 18-hole course with picturesque views, ideal for golf enthusiasts of all skill levels.
Adventure Landing Jacksonville Beach
10 minutes' drive
Family-friendly amusement park featuring water slides, laser tag, and arcade games for all ages.
Jacksonville Beach Pier
15 minutes' drive
Iconic pier with scenic views, perfect for fishing or enjoying a stroll along the waterfront.
Outdoor Exploration at Castaway Island Preserve
10 minutes' drive
Nature trails and estuaries await, great for birdwatching and leisurely walks among the wildlife.
Smoothie and Yoga at The Yoga Den
5 minutes' drive
Relaxing yoga sessions offered amidst calming scenery, perfect for stress relief and rejuvenation.
Bundy Cafe & Atrium
10 minutes' walk
Casual eatery known for its warm atmosphere and delicious breakfast options, including hearty omelets.
Marker 32
15 minutes' drive
Upscale dining with waterfront views, renowned for fresh seafood and an extensive wine list. Reservations recommended.
Regal Beach Boulevard 18
10 minutes' drive
Modern cinema featuring the latest films, comfortable seating, and occasional special screenings.
Mind Bender Escape Rooms
10 minutes' drive
Fun and challenging escape room experience perfect for families and friends looking for a night of thrills.
Local transportation
City Centre
Jacksonville35 min  ·  14.1 mi
Airports
Jacksonville International Airport (JAX)67 min  ·  27.7 mi
St. Augustine, FL (UST)71 min  ·  29.2 mi
Train
Jacksonville Electric Authority Southside Generating Station Wharf30 min  ·  12.3 mi
Union Station36 min  ·  14.9 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Pets
Pets are allowed on request.
Number of floors:
7
Number of rooms:
181
Former name
residence inn by marriott jacksonville - mayo clinic area
FAQs
About Residence Inn By Marriott Jacksonville-Mayo Clinic Area
What are the check-in and check-out times at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Check-in is at 16:00 and check-out is at 11:00.
How far is Residence Inn By Marriott Jacksonville-Mayo Clinic Area from Jacksonville International Airport?
The hotel is located 45 km from Jacksonville International Airport.
What amenities are available at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
The hotel features free Wi-Fi, free parking, a fitness center, an outdoor swimming pool, and a bar/lounge area.
Are pets allowed at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Pets are allowed at the hotel, with charges potentially applicable.
What dining options are available at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Guests can enjoy a buffet or American breakfast, and there is an on-site bar offering food service.
Is there a shuttle service available from Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
A complimentary hourly shuttle service is available from 07:00 to 17:00 for local attractions and medical facilities.
What facilities are available for business travelers at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
The hotel offers a business center, meeting spaces, and complimentary Wi-Fi throughout the property.
What recreational facilities does Residence Inn By Marriott Jacksonville-Mayo Clinic Area have?
Guests can enjoy an outdoor swimming pool and a 24-hour fitness center.
How far is Residence Inn By Marriott Jacksonville-Mayo Clinic Area from the nearest medical facility?
The hotel is a 2-minute drive, approximately less than 1 km, from Mayo Clinic Florida.
Are there laundry facilities available at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
The hotel provides laundry services for guests.
What are the room amenities at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Rooms feature air conditioning, a flat-screen TV, a seating area, and a fully equipped kitchen.
What nearby attractions can guests visit from Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Nearby attractions include St. Johns Town Center (9 minutes away by car) and Jacksonville Beach Golf Club (8 km from the hotel).

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