Residence Inn By Marriott Jacksonville-Mayo Clinic Area Fast Food photoResidence Inn By Marriott Jacksonville-Mayo Clinic Area Exterior photoResidence Inn By Marriott Jacksonville-Mayo Clinic Area Exterior photo
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From163US$ /night
Check-in
18Apr2026Select date
Check-out
19Apr2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Property overview

4905 San Pablo Road South, Jacksonville, Florida, United States, 32224
-
Near the Mayo Clinic
Great
8.8
9.3
/10
4.5
4.4
/5

Rooms and Suites

Residence Inn By Marriott Jacksonville-Mayo Clinic Area features 155 air-conditioned rooms, each equipped with a kitchen that includes a refrigerator and stovetop. Rooms include a flat-screen TV with satellite channels, a seating area, a dining area, and a private bathroom with a hairdryer and complimentary toiletries. Suites have a fully equipped kitchen, a living area, a sofabed, complimentary Wi-Fi, and a 50- or 55-inch SMART HDTV with Netflix. Certain suites also feature a dining area and tea/coffee maker.

Dining Options

Guests can enjoy a buffet or an American breakfast. A grocery/convenience store is available. The hotel has a lobby bar where guests can get a beverage and a bite to eat. There's also a poolside bar. Guests are welcome to a complimentary reception, held on select days.

Leisure and Recreation

Residence Inn By Marriott Jacksonville-Mayo Clinic Area has an outdoor swimming pool and a 24-hour fitness center. Barbecue facilities and a terrace are available. Guests can enjoy recreational amenities, including an outdoor pool and a fitness center.

Location and Transportation

Residence Inn By Marriott Jacksonville-Mayo Clinic Area is a 2-minute drive from Mayo Clinic Florida and 9 minutes from St Johns Town Center. It is 10.8 mi from Mayport Naval Station, 29 km from Union, and 45 km from Jacksonville International Airport. The hotel provides a complimentary hourly shuttle from 7 AM to 5 PM to the Mayo Clinic, which is less than 1 mile away. Nearby landmarks include Jacksonville Beach Pier (6 km), South Beach Park and Sunshine Playground (4 km), and Adventure Landing Jacksonville Beach (4 km).

Hotel Services

The accommodation features a 24-hour front desk, a shuttle service, a business centre, and complimentary Wi-Fi throughout the property. Featured amenities include a 24-hour business center, express check-out, and complimentary newspapers in the lobby. This hotel has facilities measuring 2678 square feet, including conference space. Concierge services and wedding services are available. Guests have access to laptop-compatible safes and desks, and can inquire about post-treatment nursing care partnership.

“In my opinion, this property stands out for its dedication to guest comfort, especially with suites designed for extended stays and those visiting the nearby Mayo Clinic. I particularly appreciate the pet-friendly environment and the availability of in-suite kitchens. It's my view that the focus on convenience, from complimentary breakfasts to the shuttle service, enhances its appeal for both medical and business travelers.”
Hotel logo
David MillerEditor, UsFlorida
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Choose your preferred room

The property features double rooms, family rooms, and suites, often including breakfast, free cancellation, and special offers
King Studio Hearing accessible
3 persons
1 King-size bed
Coffee machine
Heating
Corner King Studio
3 persons
1 King-size bed
Coffee machine
Heating
King Studio Mobility accessible
3 persons
1 King-size bed
Coffee machine
Heating
Corner Queen Suite
5 persons
1 Queen-size bed
Shower
Coffee machine
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Calendar of room availability and rates

See current availability and pricing for your dates

Facilities

Amenities are designed to ensure comfort and memorable stays
Facilities: Perfect
9.0/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Fireplace
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Golf course

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Free shuttle service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Grocery shopping service
  • Shops/Commercial services

Dining

  • Bar/ Lounge area
  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's buffet
  • Board games

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Heated swimming pool
  • Outdoor swimming pool
  • Sun loungers
  • BBQ facilities
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Dining table

Bathroom

  • Free toiletries
  • Sink

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Residence Inn By Marriott Jacksonville-Mayo Clinic Area Location

4905 San Pablo Road South, Jacksonville, Florida, United States, 32224
Map view
4905 San Pablo Road South, Jacksonville, Florida, United States, 32224
Nearby
Hospital
Mayo Clinic Jacksonville
3400 ft
Restaurants
Bundy Cafe & Atrium
3000 ft
4500 San Pablo Rd S Mayo Clinic
Explore Jacksonville
Local Experiences Near Residence Inn Jacksonville-Mayo Clinic Area
Top Attractions
Activities
Dining
Entertainment
Mayo Clinic Jacksonville
15 minutes' walk
Esteemed medical facility known for its advanced healthcare services, tours available for interested visitors.
Harbor City Municipal Golf Course
5 minutes' drive
Challenging 18-hole course with picturesque views, ideal for golf enthusiasts of all skill levels.
Adventure Landing Jacksonville Beach
10 minutes' drive
Family-friendly amusement park featuring water slides, laser tag, and arcade games for all ages.
Jacksonville Beach Pier
15 minutes' drive
Iconic pier with scenic views, perfect for fishing or enjoying a stroll along the waterfront.
Outdoor Exploration at Castaway Island Preserve
10 minutes' drive
Nature trails and estuaries await, great for birdwatching and leisurely walks among the wildlife.
Smoothie and Yoga at The Yoga Den
5 minutes' drive
Relaxing yoga sessions offered amidst calming scenery, perfect for stress relief and rejuvenation.
Bundy Cafe & Atrium
10 minutes' walk
Casual eatery known for its warm atmosphere and delicious breakfast options, including hearty omelets.
Marker 32
15 minutes' drive
Upscale dining with waterfront views, renowned for fresh seafood and an extensive wine list. Reservations recommended.
Regal Beach Boulevard 18
10 minutes' drive
Modern cinema featuring the latest films, comfortable seating, and occasional special screenings.
Mind Bender Escape Rooms
10 minutes' drive
Fun and challenging escape room experience perfect for families and friends looking for a night of thrills.
Local transportation
City Centre
Jacksonville35 min  ·  14.1 mi
Airports
Jacksonville International (JAX)67 min  ·  27.7 mi
St Augustine (UST)71 min  ·  29.2 mi
Train
Jacksonville Electric Authority Southside Generating Station Wharf30 min  ·  12.3 mi
Union Station36 min  ·  14.9 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Pets
Pets are allowed on request.
Number of floors:
7
Number of rooms:
181
Former name
residence inn by marriott jacksonville - mayo clinic area

Guest ratings and reviews

Guest feedback from past stays
Review score
Based on 174 verified reviews
9.3/10
Perfect
93%
Recommend
Cleanliness
9.0/10
Comfort
9.0/10
Facilities
9.0/10
Free Wi-Fi
9.5/10
Location
9.4/10
Staff
8.9/10
Value for money
8.4/10
Pros
Kitchenettes
Helpful staff
Free shuttle
Cons
Unclean bathroom
Noisy AC
Uncomfortable couch
Guest reviews
based on 271 reviews
8.8/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
FAQs
About Residence Inn By Marriott Jacksonville-Mayo Clinic Area
What are the check-in and check-out times at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Check-in is at 16:00 and check-out is at 11:00.
How far is Residence Inn By Marriott Jacksonville-Mayo Clinic Area from Jacksonville International Airport?
The hotel is located 45 km from Jacksonville International Airport.
What amenities are available at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
The hotel features free Wi-Fi, free parking, a fitness center, an outdoor swimming pool, and a bar/lounge area.
Are pets allowed at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Pets are allowed at the hotel, with charges potentially applicable.
What dining options are available at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Guests can enjoy a buffet or American breakfast, and there is an on-site bar offering food service.
Is there a shuttle service available from Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
A complimentary hourly shuttle service is available from 07:00 to 17:00 for local attractions and medical facilities.
What facilities are available for business travelers at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
The hotel offers a business center, meeting spaces, and complimentary Wi-Fi throughout the property.
What recreational facilities does Residence Inn By Marriott Jacksonville-Mayo Clinic Area have?
Guests can enjoy an outdoor swimming pool and a 24-hour fitness center.
How far is Residence Inn By Marriott Jacksonville-Mayo Clinic Area from the nearest medical facility?
The hotel is a 2-minute drive, approximately less than 1 km, from Mayo Clinic Florida.
Are there laundry facilities available at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
The hotel provides laundry services for guests.
What are the room amenities at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Rooms feature air conditioning, a flat-screen TV, a seating area, and a fully equipped kitchen.
What nearby attractions can guests visit from Residence Inn By Marriott Jacksonville-Mayo Clinic Area?
Nearby attractions include St. Johns Town Center (9 minutes away by car) and Jacksonville Beach Golf Club (8 km from the hotel).

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Rooms and Guests2 Guests, 1 Room