The Panacea Motel Exterior photo This is a bright, sunny photograph featuring a charming, colorful single-story building set in a lush, tropical environment.

The main structure has a light-colored, possibly cream or white, exterior with vertical siding. A prominent feature is a lonThe Panacea Motel Exterior photo This is a photo of a small, rectangular doormat placed on an outdoor wooden deck.

The doormat is a coarse, brown, coir (coconut fiber) material and features a hand-lettered message in the center that reads: **"yay it's you"**. The text is written inThe Panacea Motel Exterior photo This is a photograph of a rustic, wooded property, likely a rural home or cabin setting.

**Key elements in the image include:**

*   **The House:** On the right side of the frame is a light blue or pale gray siding house. It has white-framed windows
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Check rooms and rates
From131US$ /night
Check-in
26May2026Select date
Check-out
27May2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Property overview

1545 Coastal Highway, Panacea, Florida, United States, FL 32346
-
Near the beach
Great
8.5
8.9
/10
4.7
4.7
/5

Rooms at Panacea Motel

The Panacea Motel provides rooms that include a flat-screen TV and air conditioning. Rooms also have a private bathroom equipped with a shower. Options range from double rooms to studios and bungalows. Some rooms offer soundproof walls, a tea and coffee maker, and an inner courtyard view. Select rooms feature a washing machine. Each room has its own unique decor inspired by a fresh, coastal beach style. Larger properties feature king beds and more space.

Dining Near The Motel

Angelo's, a fine dining restaurant on the river, offers a nice dining experience. Posey's Up the Creek Steam Room, within walking distance, serves seafood at reasonable prices. Seineyard Seafood is located next door to the Marina.

Leisure and Activities

Guests can enjoy activities like fishing and canoeing in and around Panacea. The motel provides a private trail to the bay. Wakulla Springs, St Mark's Lighthouse, St George Island, and Apalachicola are accessible for day trips. Mashes Sand Beach, 10 minutes from the motel, is suited for sand and water activities. Guests may also visit St George Island, approximately one hour away. Other options include Gulf Specimen Public Aquarum (2 km), Otter Lake (3 km), Woolley Park (2 km), and Dickerson Bay (2 km).

Location and Access

The Panacea Motel has a central location for many attractions. Tallahassee is 40 minutes away. The Tallahassee Museum of History and Natural Science is 49 km from the property. Tallahassee International Airport is 50 km away.

Motel Services

The Panacea Motel provides private entrances and free Wi-Fi in rooms. Additional services include analysis or valuable information and customer care support. The motel also provides ADA accessible units. Pets are accommodated. Other services available include: To provide and maintain the Service. To notify you about changes to our Service. To allow you to participate in interactive features of our Service when you choose to do so. To provide customer care and support. To provide analysis or valuable information so that we can improve the Service. To monitor the usage of the Service. To detect, prevent and address technical issues. To prevent or investigate possible wrongdoing in connection with the Service.

“There's a distinct charm to be found here; the kind that makes you want to explore Florida's Forgotten Coast. The coastal-inspired decor is a nice touch, and the private bay trail adds an unexpected element of nature. It strikes me as a solid choice for those wanting to unwind and get a little closer to the outdoors.”
Hotel logo
David MillerEditor, UsFlorida
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Choose your preferred room

The property features double rooms, family rooms, and suites, often including breakfast, free cancellation, and special offers
Deluxe King Room
2 persons
305 sq. feet 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
305 sq. feet 
2 King Size Beds
Shower
Coffee machine
Deluxe Double Room
2 persons
305 sq. feet 
2 King Size Beds
Shower
Coffee machine
Queen Studio
2 persons
305 sq. feet 
1 King-size bed
Shower
Coffee machine
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Calendar of room availability and rates

See current availability and pricing for your dates

Facilities

Amenities are designed to ensure comfort and memorable stays
Facilities: Great
8.6/10Review score

General

  • No smoking on site
  • Parking
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Vending machines
  • Fireplace
  • Smoke detectors
  • Fire extinguishers

Sports & Fitness

  • Canoeing
  • Fishing

Guest Parking

  • Dryer
  • Cookware/ Kitchen utensils

Dining

  • Picnic area/ Tables

Room features

  • Free Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Patio
  • Garden furniture
  • Tea and coffee facilities
  • Dining table

Bathroom

  • Washing machine

Self-catering

  • Dryer
  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
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The Panacea Motel Location

1545 Coastal Highway, Panacea, Florida, United States, FL 32346
Map view
1545 Coastal Highway, Panacea, Florida, United States, FL 32346
Restaurants
Posey's Up the Creek Steam Room
2400 ft
1506 Coastal Hwy
Explore Panacea
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Gulf Specimen Public Aquarium
25 minutes walking
Marine life exhibits and educational programs showcase local ecosystems. Family-friendly and great for kids of all ages.
Woolley Park
20 minutes walking
Community park featuring playgrounds, picnic areas, and a walking trail. Ideal for family outings and relaxation.
Dickerson Bay
25 minutes walking
Scenic bay area offering fishing opportunities and beautiful views. Perfect for nature lovers and picturesque sunsets.
Kayaking at Dickerson Bay
25 minutes walking
Guided kayaking tours let you explore local waters. Rentals available nearby; suitable for both novices and experienced paddlers.
Fishing at Gulf Specimen
25 minutes walking
Fishing opportunities at this educational aquarium. Visitors can engage with local marine wildlife while casting a line.
Posey's Up the Creek Steam Room
9 minutes walking
Casual seafood restaurant famous for fresh catches and local flavors. Enjoy outdoor seating with a view of the creek.
Live Music at Rivers Edge
5 minutes driving
Local bar featuring live music events weekly. Great vibe for both families and adults looking for a fun night out.
Local transportation
City Centre
Panacea8 min  ·  3.3 mi
Airports
Tallahassee Regional (TLH)72 min  ·  29.8 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Internet
Wireless internet is available in the hotel rooms for free.
Pets
Pets are allowed on request.
Number of rooms:
92

Guest ratings and reviews

Guest feedback from past stays
Review score
Based on 193 verified reviews
8.9/10
Great
88%
Recommend
Cleanliness
8.9/10
Comfort
9.0/10
Facilities
8.6/10
Free Wi-Fi
8.3/10
Location
8.5/10
Paid Wi-Fi
5.0/10
Staff
8.9/10
Value for money
8.5/10
Pros
Cute hotel
Cozy chairs
Nice location
Cons
Musty odor
Noisy street
Non-working outlet
Guest reviews
based on 95 reviews
8.5/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About The Panacea Motel
What are the check-in and check-out times at The Panacea Motel?
Check-in is at 16:00 and check-out is at 11:00.
How far is The Panacea Motel from Tallahassee Regional Airport?
The hotel is located 42 km from Tallahassee Regional Airport.
Is there free parking available at The Panacea Motel?
Free private parking is available on-site without the need for a reservation.
What activities can guests enjoy at The Panacea Motel?
Guests can participate in fishing and canoeing activities in and around Panacea.
What dining options are available near The Panacea Motel?
Fine dining options nearby include Angelo's restaurant located right on the river.
What amenities are included in the rooms at The Panacea Motel?
Rooms feature air conditioning, a flat-screen TV, a coffee machine, and a private bathroom.
What attractions are close to The Panacea Motel?
Nearby attractions include Wakulla Springs, St George Island, and Tallahassee Museum of History and Natural Science, which is 49 km away.
What types of room amenities are available at The Panacea Motel?
Rooms include a refrigerator and tea or coffee making equipment for convenience.
Are there any unique features of the rooms at The Panacea Motel?
Some rooms come with a patio, and spacious bungalows offer soundproof walls and inner courtyard views.

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